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Description

Conclusive evidence shows that ApoE4 contributes to the development of AD, likely through both a loss-of-function in neuroprotection and a gain-of-function in neurotoxicity, when compared to ApoE3 (Huang and Mucke, 2012

Lackner KJ

doi: 10.1111/j.1462-5822.2009.01409.x 142 LumsdenR

Analysis of data extracted from multiple databases, including the Centers for Medicare and Medicaid Services, National Center for Health Statistics, Medical Expenditure Panel Survey, NHANES, Department of Veterans Affairs, National Association of Children's Hospitals and Related Institutions, and various private data sets between 1994 and 2000 revealed an increase of 29% from $37 to $66 million among persons with a formal diagnosis of IC/BPS