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doi: 10.1016/S0025-326X(97)87421-8 126 TomM.AuslanderM

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47 In addition, rodent GH does not activate the human or primate GHR, so the use of pegvisomant in animal models of disease does not address the effect of the blockade of systemic GH

Ferroptosis, an iron-dependent form of regulated cell death driven by lipid peroxidation, has emerged as a pivotal regulator of tumor progression and treatment response, offering new avenues to overcome current limitations, such as drug resistance and low response rates