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To minimize assessment bias, all imaging evaluations were performed by two independent spine surgeons who were blinded to the patients clinical information

10.1128/AEM.0267614 98

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With mutagenesis studies, we propose an acyl-modification driven ghrelin-binding model, in which the binding of octanoyl group in cavity II orients the N-terminus of ghrelin to cavity I, and leads to the initiation of signal transduction