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Arthritis Res Ther (2010) 12(2):206

2-Cyclohexyl-4-isopropyl-N-(4-methoxybenzyl) aniline, known as CIMBA, reduces the expression of proinflammatory factors and alleviates cholangitis in cholangiocytes by inhibiting the GPER/NF-B pathway [280]

3,4 Dysregulated biological processes, cellular senescence, cytokine disequilibrium, tissue impairment and skeletal fracture are responsible for age-related degeneration and dysfunction, resulting in degenerative intervertebral discs, degraded articular cartilage, and loss of bone

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