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In addition to increased ROS and lipid ROS [122], the levels of intracellular iron can also be augmented after IL- 1 treatment in chondrocytes

The epidemiological data presented in Table 1 sheds light on the prevalence of DPN and painful DPN, and the percentage of undiagnosed DPN and painful DPN among these patients [5, 8, 24,25,26,27,28,29,30,31,32]