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Description

Relapse occurs in part due to the redox-induced dedifferentiation of non-GSCs that would add to this therapy resistance (Bao et al., Quite a few other mechanisms could be responsible, including OS, which would modulate the efficacy of treatments and resistance in various ways, impacting on drug sensitivity, apoptosis, angiogenesis, or inflammatory pathways (Nathan and Cunningham-Bussel, 2013)