l-carnitine shuttles fatty acids into mitochondria Carnitine Shuttle Carnitine Shuttle and Fatty Acid

Funding This research was supported by the National Institutes of Health Grants: R01-DK088139 (PJR), R01-HD093701 (PJR), T32HD007186 (JS, AW trainees, PJR PD), R01-HD079404 (LDB)

The most serious clinical complication of DVT is pulmonary embolism (PE), which has a high mortality rate

In the early stages of metastasis, autophagy primarily inhibits the EMT programme, and later, metastatic cells may require sustained autophagy for survival under environmental and metabolic stress conditions (111) ( Figure 4 )

For understanding the binding of the four selected compounds to GPX4 protein showing the mechanism of the interaction, molecular docking analysis and molecular dynamic (MD) simulation were used