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Conflict of interest General sources of potential conflict of interest, considered unrelated to this work include the following: AM has received fees as consultant and/or advisor to Janssen Pharmaceutica NV, Gedeon Bulgaria, Pierre Fabre, and Lundbeck

IV magnesium sulphate has been studied as a treatment for migraine in emergency department settings and is effective, comparable to other IV medications (metoclopramide, prochlorperazine, caffeine citrate), well tolerated and has a good safety profile

Of note, the World Health Organization considers vitamin A deficiency in a population to be a moderate public health problem when the prevalence of low serum retinol ( 50 years) Presently, there is little evidence that the requirement for vitamin A in older adults differs from that of younger adults

GAPDH, glyceraldehyde 3 phosphate dehydrogenase