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This schedule is consistent across all months of the cycle

This cascade leads to neuronal apoptosis and energy deficits, particularly in the prefrontal cortex and hippocampus ( 4.3 Excitotoxicity Synthetic cathinones disrupt glutamatergic signaling by enhancing glutamate release and impairing astrocytic uptake (Zhang and Bhavnani, 2006)

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Besides their autocrine/paracrine and structural roles, brain pericyte also engage in crosstalk with brain microvascular endothelial cells, promoted in part via gap junctions between the cells