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Probiotics, which are capable of colonizing the intestinal tract, are reported to improve metabolic diseases such as obesity and diabetes through modulating intestinal microorganisms [22,23,24]

Friard O, Gamba M

Indeed, since the 1960s the brain was almost axiomatically viewed as an immune-privileged site [473]

The author suggested that green tea polyphenols can be indeed regarded as potential therapeutic agents to treat diseases with chronic inflammation at their epicentre, such as inflammatory bowel diseases, gastrointestinal malignancies, and neurodegenerative disorders