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Kantamneni et al., 2014)

10.5455/njppp.2020.10.1239503012020 234 VitaleP.BraghettaP.VolpinD.BonaldoP.BressanG

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coli O55:B5 could activate most of microglia in the rat brain microvascular endothelial cell (RBEC)/microglial co-culture system at 6 hours, which appeared as a morphological change from round to bipolar rod shape with enlarged cytoplasm and cell bodies, and an enhanced ionized calcium binding adapter molecule 1 (Iba1) staining (Nishioku et al., 2009