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These codes are particularly relevant for patients on tirzepatide because nutritional guidance is a key component of maximizing treatment outcomes

Nonetheless, this work has identified novel findings that support future studies to determine whether microbiome changes are contingent upon the combination of both NNMTi and LD switch and mediated through direct NNMTi-driven mechanisms or through indirect mechanisms such as weight or fat loss 8,13

For those with neuropsychiatric symptoms from low B12, these findings offer hope and a clear path to getting better

Acceleration Support scheme supported by funding from MRC IAA 2021 UCL MR/X502984/1