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In the end, I suggest there are two simple rules of thumb: (1) Start treatment if the acetaminophen concentration or the transaminase are elevated and (2) stop treatment when the serum acetaminophen is non-detectable and the transaminase are normal

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Bertino L, Guarneri F, Cannavo SP, Casciaro M, Pioggia G, Gangemi S (2020) Oxidative stress and atopic dermatitis

This letter in a narrow respect validates, at least anecdodately, the core argument firms like Novo Nordisk and Eli Lilly are making: that compounded versions of their drugs, produced outside a more robust CGMP framework, carry real and documented patient safety risks