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However, these potential benefits have not yet been fully backed by clinical research, and the safety of long-term use remains questionable

The supraspinatus tendon, the most commonly injured rotator cuff structure, has a particularly poor vascular zone near its insertion point on the humerus

This is exemplified by the exclusion of albumin, but not IgG across placental tissue, and by higher FcRn-mediated transcytotic rates of albumin than IgG at certain mucosal surfaces [17, 82,83,84,85]