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Aggrecan is a critical proteoglycan for maintaining disc hydration and shock-absorbing capacity

Access this chapter Subscribe and save Buy Now Tax calculation will be finalised at checkout Purchases are for personal use only Similar content being viewed by others Abbreviations ASD: autism spectrum disorder BDNF: Brain-Derived Neurotrophic Factor C1q: complement component 1q C3: complement component 3 Ca 2+ : calcium CaMKII: calcium/calmodulin-dependent kinase II CASK: calcium/calmodulin-dependent serine protein kinase Cbln1: cerebellin 1 precursor protein Cl: chloride CNS: central nervous system CR3: complement receptor 3 E/I: excitatory/inhibitory ECM: extracellular matrix FGF: fibroblast growth factor FMRP: Fragile X Mental Retardation Protein GABA: gamma-aminobutyric acid GluR2: glutamate receptor-like molecule 2 LGN: Lateral Geniculate Nucleus MAGUK: Membrane-associated Guanylate Kinase MEF2c: myocyte enhancer factor 2c MEGF10: multiple EGF-like domains 10 mRNA: messenger RNA Munc13: Mammalian Homolog of Unc13 MuSK: Muscle specific kinase Na+: sodium NCAM: neural cell adhesion molecule NMDA: N-methyl-D-aspartate NMJ: neuromuscular junction Pcdh10: protocadherin 10 PSD: postsynaptic density PSD-95: postsynaptic density protein-95 RGCs: retinal ganglion cells RIM-BPs: RIM-Binding Proteins RIMs: Rab3A-Interacting Molecules SM: Sec1/Munc18-like SNARE: SNAP receptor TREM2: triggering receptor expressed on myeloid cells 2 TSP2: thrombospondin-2 References Ressot C, Bruzzone R

To visualize the fine structure of ER distinctly and confirm the colocalization, a region of interest (ROI) magnified using confocal zoom was analyzed as shown in Fig

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