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10.1097/brs.0b013e3181624504 139 KrausP.LiK.SipesD.VardenL.YerdenR.HendersonA.et al (2019)

Where the Science Still Has Gaps Several questions remain unresolved: optimal dosing for therapeutic applications long-term systemic safety standardized clinical protocols large randomized human trials These gaps highlight the difference between promising experimental science and established clinical practice