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RSC Med Chem 15(12):39503969

doi: 10.1016/j.nut.2016.10.003 297 BelarbiYMejhertNLorente-CebrinSDahlmanIArnerPRydnMet al

Parental and GOT1/2 dKO cells were grown in RPMI medium for 14 population doublings in the presence and absence of pyruvate after which the sgRNA repertoire was profiled by next generation sequencing (Fig