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In contrast, overexpressing SIRT2 in SIRT2-low cell lines (786-O, ACHN) markedly enhanced cellular GSH level and synthesis rate (Figs

p140Cap, a multisite docking protein co-distributed with cortical actin and actin stress fibers and absent in FA [90], is regulated by several miRNAs [91]

Mass spectrometry parameters were: scan range m/z 100-1000

LC-MS/MS analysis An LC-MS/MS analysis was performed for each fraction using an Orbitrap Eclipse Tribrid mass spectrometer (Thermo Fisher Scientific), which was equipped with FAIMS (Field Asymmetric Ion Mobility Spectrometry)