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The two-hit vascular hypothesis of Alzheimer's disease proposes that BBB dysfunction allows neurotoxins to enter the brain parenchyma, which in turn leads to neuroinflammation[43]

CaOx-stimulated exosomes from TCMK-1 cells promoted M1 polarization TCMK-1 cells were stimulated by 150mmol/ml CaOx, with or without the exosome secretion inhibitor GW4869, for 24 h

Structured from the figure, the GSH and other peptide and protein is different, it's a special peptide bond in the molecule,by glutamate gamma carboxyl (-COOH) and alpha amino-cysteine (NH2) peptidebond condensation

Triphala has antibacterial, anti-inflammatory and anti-diarrheal abilities