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Oxidative and ER stresses largely contribute to ZEN-induced apoptosis, with Se shown to significantly prevent the same in chicken spleen lymphocytes by improving the ER stress signaling pathway (153)

bei chronischer Erschpfung, mitochondrialer Dysfunktion oder Stressbelastungen angepasst

Overexpression of insulin-like growth factor-binding protein-4 (IGFBP-4) in smooth muscle cells of transgenic mice through a smooth muscle -actinIGFBP-4 fusion gene induces smooth muscle hypoplasia

In neurons, iron overload, generally in the form of Fe 2+ , can trigger the Fenton reaction, resulting in lipid peroxidation and neuronal ferroptosis (Jacquemyn et al