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Description

To better understand the effect of RSL3 on LMP, we monitored the release of FITC-dextran (40 kDa), which accumulates in lysosomes through endocytosis

a history of an allergic reaction to ofatumumab, the active ingredient in Kesimpta

This mechanistic distinction suggests the two agents could be synergistic rather than redundant, though that hypothesis has not been tested in a published clinical trial as of January 2025