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The symptoms of B12 deficiency are varied and may include: Numbness or tingling in your limbs Depression or paranoia Pale skin Mouth sores Abnormal reflexes General feeling of weakness Memory loss or confusion B12 Deficiency Can Put You in Jeopardy A B12 deficiency can cause a specific form of anemia called pernicious anemia

Early studies revealed that the neuropeptides delivered orally in this way had a pharmacodynamic profile consistent with the reported pharmacology, were rapidly absorbed by the gastrointestinal tract, and reached concentrations several-fold higher than those seen naturally postprandially (128)

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Patients often notice this benefit within the first few weeks, before other changes become visible