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Symptoms include: Mouth ulcers Burning tongue Smooth red tongue Pain while eating spicy food Sometimes dentists are the first to suspect low B12

Circulation 107:13591365 Yasumura EG, Stilhano RS, Samoto VY, Matsumoto PK, de Carvalho LP, Valero Lapchik VB, Han SW (2012) Treatment of mouse limb ischemia with an integrative hypoxia-responsive vector expressing the vascular endothelial growth factor gene

Occasionally, individuals experience temporary minor discomfort or sensitivity at injury sites during early treatment

It is thought that this side effect is caused by the drugs ability to alter serotonin levels and affect neurons in the brain, which can lead to a seizure disorder