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While one study revealed smaller infarct sizes in MI patients treated with colchicine, two other recent trials failed to document a clear benefit of colchicine in the acute stetting ( Conclusion Taken together, our data suggest that colchicine an inhibitor of microtubule assembly with anti-inflammatory properties reduces vascular inflammation and plaque progression by silencing monocyte and neutrophil activation and thereby preventing uptake of these cells into atherosclerotic plaques

These compounds appear in the published cellular-biology, NAD redox, telomere-biology and senescence research literature in pre-clinical, in-vitro and animal model systems

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Others don't get enough B12 from their food, which could require vitamin B12 injections to maintain a healthy level