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Maturitas 144, 108111 10.1016/j.maturitas.2020.08.007 [DOI] [PMC free article] [PubMed] [Google Scholar] 138.Al Sulaiman K., Aljuhani O., Al Dossari M.et al

Subsequent work established that the peptide was naturally complexed with copper in plasma and that both the peptide and the copper were necessary for its biological effects

PloS one 12 , e0176883 (2017)

In summary, insulin-related genes affect spermatogenesis and function through multiple mechanisms, directly participating in the spermatogenesis process and indirectly influencing sperm development through metabolic pathways and epigenetic modifications