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Two As species, sodium arsenite and DMA, induced apoptosis in cultured neurons of rat brain via activation of p38 and JNK3 MAP kinases, two enzymes that are activated by stress signals and mediate neuron apoptosis

Ophthalmology 115 , 597598 (2008)

Another possibility is the following: after uptake, vitamin B12 is slowly bound to serum vitamin B12 proteins ( The mechanism by which vitamin B12 administration exerts its positive effect on ME/CFS patients is unknown