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Rapid Covalent-Probe Discovery by Electrophile-Fragment Screening

Cell staining with fluorescently-labeled Pin1- and PKC-specific Abs and analysis using a confocal microscope we observed that in a fraction of antigen (HA peptide 307-319) -pulsed LG2 cells that formed conjugates with the CH7C17 T cells, Pin1 and PKC colocalized at the T cell-APC contact area ( Figure 5C )

No magic cure but these peptides gave me my livelihood back way faster than waiting around would have

Justin Lathia, PhD: But to expand on what Ofer said is that once you have this idea of what's in the complex, what the complex looks like, a similar strategy using peptides could be leveraged quite easily actually