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12 In a controlled trial in 60 healthy adults with moderate-to-high perceived stress levels, those receiving 225 mg or 400 mg of ashwagandha daily for 30 days performed better on various cognitive tests at the end than at the beginning of the trial, although the improvements were not significantly different from those seen with placebo

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It is also of great importance to replicate the current work in an adolescent female model given that females may respond differently to drugs of abuse when compared to males 90

Effects of dietary supplementation of carnosine on mitochondrial dysfunction, amyloid pathology, and cognitive deficits in 3xTg-AD mice