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We hypothesized that the hepatic metabolome would be similarly characterized by increased alternative energy pathway utilization, altered redox balance and glutathione depletion, and reduced levels of ATP

MSM supplies organic sulfur, an essential component of collagen, cartilage, tendons, ligaments, and other connective tissues

GSH concentrations and OxS RBC total and reduced GSH concentrations were measured by liquid chromatography (Waters ACQUITY UPLC System), and concentrations of oxidized glutathione (GSSG) calculated as the difference between total and reduced GSH

Since regular alcohol exposure depletes glutathione, taking a glutathione supplement makes sense