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Co-toxicity of Endotoxin and Indoxyl Sulfate, Gut-Derived Bacterial Metabolites, to Vascular Endothelial Cells in Coronary Arterial Disease Accompanied by Gut Dysbiosis

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Current therapies under investigation (Table 8) are targeting muscle-specific kinase (MuSK), which promotes post-synaptic clustering, synaptogenesis via F-actin branching and dendritic proliferation [293], and reduction of aberrant sphingolipid regulation to promote NMJ stability [294]

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