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Indeed, over-administration of APAP resulted in GSH depletion

Epidemiological studies suggest that offspring of T2DM patients may have an elevated metabolic risk for oxidative stress and iron-mediated cardiovascular disease, potentially due to the inheritance of specific genes [73,74,75,76]

Blocking EAAT2 resulted in the replacement of STDP with a timing-independent, non-Hebbian form of plasticity that also did not require the usual order of activity (i.e., pre-synaptic before post-synaptic spikes)