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Amongst those virulence factors, several bacterial E3 ubiquitin ligases were reported 10,11,12,13,14,15

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Cell Metab 23:303314 Xu C, Wang L, Fozouni P, Evjen G, Chandra V, Jiang J, Lu C, Nicastri M, Bretz C, Winkler JD et al (2020) SIRT1 is downregulated by autophagy in senescence and ageing