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Recent research in this area enthusiastically recognizes extracellular vesicles (EVs) from human liquid biopsy as intriguing sources to differentiate disease from healthy states 109,110

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Many different conditions affect the contents of intracellular GSH, some of them are the presence of heavy metals, high glucose concentrations, protein malnutrition, thermal shock, exposure to reactive oxygen and nitrogen species including, H 2 O 2 and nitric oxide, ozone exposure, ionizing radiation, and cigarette smoke [37,40,61,73,81]