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Macrophage DCLK1 promotes atherosclerosis via binding to IKK and inducing inflammatory responses

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Through directly neutralizing the free radicals, regenerating other endogenous antioxidants (such as glutathione, vitamins C and E, and coenzyme Q10), and chelating the redox-active metal ions (e.g., Fe 2+ ), ALA could mitigate the Fenton reaction-mediated oxidative damage, thereby amplifying its powerful anti-oxidative activity (1315)

However, despite these substances are able to interfere with iodine uptake in the thyroid, the consumption of reasonable amounts of foods containing goitrogens is not a concern for people who have adequate iodine intakes and eat a variety of foods, and there are no contraindications to their consumption, as detailed below [53]