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10.1016/j.mam.2021.101052 56 SuH.LiuX.DuJ.DengX.FanY

QC has a very low oral bioavailability due to its water-insoluble property that limits its clinical application as a therapeutic agent

Statements Author contributions ZL: Writing original draft, Writing review & editing

This adaptive capacity is further complicated by the dynamic and heterogeneous nature of the AML epigenome, which varies both between patients and within individual patients over disease progression (Stelmach and Trumpp, 2023)