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These antibiotics accumulate within the endolymph, preferentially damaging outer hair cells in the basal cochlea, which results in high-frequency hearing loss, often the first detectable sign of aminoglycoside-induced ototoxicity (OSullivan et al

A half-life greater than 5 hours results in a stable signal, enabling batch processing of many plates at once using the GSH-Glo Assay

2 Ultrasound used to be a mainstay in evaluating the eye, but ever since optical coherence tomography came along, people tend to default to that rather than use ultrasound to image the structures within the eye

Treatment was initiated in mice when they displayed clinical signs characteristic of intestinal tumour burden as defined in the relevant licensing documents (for example, hunching, bloody stools)