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Hepatology 12 : 12341239 Martins da Costa C et al

Patients focused on long-term metabolic health sometimes pair MOTS-c with GHK-Cu, a copper peptide that targets tissue repair, collagen production, and anti-aging at the cellular matrix level through a completely separate mechanism

111 Additionally, enhanced PKM2-mediated glycolysis in pancreatic cancer promotes Snail lactylation and its nuclear translocation, boosting N-cadherin and vimentin expression, and eventually promoting EMT and pancreatic cancer progression