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A novel proteomic approach to the identification of endocytic cargos highlights 1 integrins as the main clients of DAB2-regulated, clathrin-dependent internalization

Some patients receive weekly infusions initially, followed by maintenance treatments as recommended

Therapies that rely on scaffold-free cellular approaches, such as ACI, are not designed to handle these mechanical burdens early post-surgery, and thus, utilizing scaffolds with improved bulk mechanical properties could increase efficacy of treatment and promote earlier return to normal activity in these knees

Under normal circumstances total body water levels are tightly regulated through the management of the pressure of intra and extra cellular fluid (comprising the intra and extra cellular water)