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[DOI] [Google Scholar] 359.Yoshii F., Zhao L., Wach R.A., Nagasawa N., Mitomo H., Kume T

Clinical efficacy is more established in UC patients, while the therapeutic effects in CD patients require further validation

Many studies have indicated that tumor tissue is a constantly evolving ecosystem contained a wide variety of cells with different phenotypes and mutations, such as cancer cells, tumor-associated fibroblasts, immune cells, cells related to blood vessels and so on, the gene mutations and epigenetic regulation of which caused by WM treatment could synergistically promote drug resistance and immune escape of cancer cells by rebuilding tumor microenvironment (TME)

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