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Antimicrobials As aforementioned, not only certain drugs used in BD exerted antimicrobial activity, but also antimicrobials could have noteworthy effects on mental functioning, because of their direct effect on gut microbiota

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for a more detailed coverage, see Anders (2008)

Noteworthy, the relative phases between p21 and Cyclin D expression profiles were significantly altered in PER2 allele mutant mouse embryonic fibroblasts, thus indicating that alteration of p21 phase, due to mutation, might impact on cell phase locking, thereby triggering cell cycle progression