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Patients with autoimmune disease that required systemic therapy within 2 years of treatment

While it produced fewer side effects, it is not as effective for as long a period as the double-shot Shingrix vaccine and is not suitable for people with immunosuppression or immune diseases

In the literature, it is frequently discussed for its possible role in soft-tissue healing , angiogenic signalling , fibroblast activity , and tendon-related repair processes