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Description

In particular, [ 68 Ga]Ga-NOTA-Nb1053 showed to be able to identify tumor infiltration in the bone marrow before the presence of overt bone damage

Reactions were performed with 50 M RHKKAc, a fluorogenic peptide substrate from p53 residues 379382, 500 M NAD + co-substrate, and recombinant human SIRT-1 (NAD + -dependent) enzyme