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For patients with known comorbidities, medical clearance is needed before each session

This study showed that pelvic irradiation can substantially promote pyknosis in the neurons of DG and CA2 regions of the hippocampus, which strongly supports that pelvic irradiation can cause memory and cognitive effects indirectly

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J Neuroinfect Dis 5:110 Li J-M, Zhao Y, Sun Y, Kong L-D (2020) Potential effect of herbal antidepressants on cognitive deficit: pharmacological activity and possible molecular mechanism