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Collectively, our findings demonstrate that GGCT can coordinately regulate both Gln and Glc metabolism and drives cell proliferation via two distinct mechanisms

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New biologics and targeted therapies in SLE target a broad spectrum of key immune players, including B/T lymphocytes, plasmacytoid dendritic cells (pDC), plasma cells, T/B cell co-stimulation molecules, cytokines or their receptors, and various intracellular signaling pathways