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Implications for management and future directions The reclassification from variants of uncertain significance to either pathogenic or likely pathogenic in accordance with ACMG guidelines, establishing a definitive diagnosis for an individual, is important for appropriate management, predictive testing for other family members, and the availability of reproductive options such as preimplantation genetic diagnosis (PGD)

2024 Mar 30;13(4):425

doi:10.1196/annals.1320.002

Though in relation to protein and amino acid metabolism, further study of creatinine metabolism, renal function, and oxidative status in dogs fed plant-based diets is warranted