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Melatonin helps maintain oocyte integrity and functionality by scavenging ROS and enhancing endogenous antioxidant enzyme activity ( Recent studies have also shown that melatonin can improve the survival and developmental competence of oocytes derived from small antral follicles (89)

Studies have demonstrated that glutathione lessens cell damage in alcoholic and non-alcoholic fatty liver diseases

[,] Owing to acute liver failure, chronic hepatitis, or cirrhosis, the clearance of ammonia by the liver is diminished, they may reach to the brain, the elevated levels of ammonia and an inflammatory response work in synergy to cause astrocytes to swell and fluid to accumulate in the brain (cerebral edema), thus, affect cerebral function [,] [Figure 7]

High blood glucose levels can trigger oxidative stress (OS), a state of imbalance between oxidation and the antioxidant defence system in the body []