nac l cysteine glutathione N-Acetyl Cysteine (Glutathione Precursor)

Tumor molecular profiling of responders and non-responders following pembrolizumab monotherapy in chemotherapy resistant advanced cervical cancer

4 Current status of GPx4 drug development In recent years, with the continuous deepening of the research on ferroptosis mechanism, targeting GPx4, as the core protein of ferroptosis regulation, has become a highly promising therapeutic strategy

This cell death paradigm manifests distinct ultrastructural features, including mitochondrial volume reduction with cristae diminution and elevated membrane electron density, while the nuclear architecture remains unaltered

Abou-Ghali and Stiban, 2015)