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[DOI] [PMC free article] [PubMed] [Google Scholar] Dai DF, Hsieh EJ, Liu Y, Chen T, Beyer RP, Chin MT, MacCoss MJ, Rabinovitch PS

For instance, co-administration of the OXPHOS inhibitor IACS-010759 with PI3K/Akt/mTOR inhibitors concurrently disrupts energy production and survival signaling, substantially reducing the tumors capacity for metabolic adaptation [128]