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HUVECs were incubated with p-cresol at 25 g/mL for 24 h, resulting in the generation of EMVs, which interfere with endothelial repair processes by decreasing the migratory capacity and the ability to form new vessels and by increasing cell senescence

Label with date and refrigerate at 28 C (35.646.4 F) , protected from light

In SURPASS-2, the rates of all reported GI side effectsincluding nausea, diarrhoea, vomiting, dyspepsia, decreased appetite, constipation and abdominal painoccurring with tirzepatide (4044.9%) were generally comparable to those seen with semaglutide (41.2%) [9]