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E.g., the stimulation of the sigma-1 receptor activates autophagy, alleviates chronic CNS inflammation by reducing immune response, and is a promising therapeutic target against

The preclinical study, published in the Journal of Nanobiotechnology, was led by Associate Professor Chester Lee Drum, Department of Medicine and the Cardiovascular-Metabolic Disease Translational Research Programme (TRP), NUS Medicine, together with co-first authors Dr Muthu Kumaraswamy Shanmugam and Dr Girish Vallerinteavide Mavelli, both Senior Research Fellows at the Department of Medicine, NUS Medicine

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